植物内生真菌生物活性成分研究进展

Research advances of endophytic fungi bioactive components

植物内生真菌是寄居植物组织内,与植物共生的真菌种类。植物内生真菌的次生代谢产物具有结构和生物活性多样性的特点,因而可为医药及农药创制提供先导结构,具有巨大的研究和开发价值。本文综述了近三年来(2017~2019年)从植物内生真菌中分离出来的具有生物活性的生物碱、聚酮、萜类、甾醇、蒽醌以及其他类化合物,并分别简要概述了其生物活性研究进展,以期为植物内生真菌活性代谢产物的研究与利用提供参考。

Endophytic fungi live in the plant tissue and coexists with the plan.The secondary metabolites of plant endophytic fungi have the characteristics of structure and bioactive diversity,so they can provide a leading structure for the creation of medicine and pesticides,and have great research and development value.In this paper,the biologically active alkaloids,polyketones,terpenes,sterols,anthraquinones,and other compounds isolated from plant endophytic fungi in recent three years(2017-2019)were reviewed,and the research progress of their bioactivity was briefly summarized,in order to provide reference for the research and utilization of the bioactive metabolites of endophytic fungi.