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重新认识血清糖类抗原72-4的临床应用价值 被引量:5

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摘要 糖类抗原72-4(CA72-4)是目前临床上应用较多的1种肿瘤标志物,最早用于胃癌和卵巢癌的辅助诊断和病情监测,可单独或联合其他肿瘤标志物用于结直肠癌、胰腺癌、肺癌、乳腺癌等恶性肿瘤的诊断和随访监测。然而,在临床实践中,CA72-4诊断恶性肿瘤的灵敏度和特异度均偏低,其水平在胃肠息肉、2型糖尿病、结缔组织病等良性疾病,以及服用秋水仙碱、灵芝孢子等药物时也可升高,可能对临床决策产生误导。因此,应重新认识CA72-4的应用价值,以更好地指导临床决策和肿瘤筛查。
作者 刘国珍 林勇
出处 《中华消化杂志》 CAS CSCD 北大核心 2020年第7期500-502,共3页 Chinese Journal of Digestion
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