经腹超声引导聚桂醇辅助射频消融术治疗子宫肌瘤对患者血流分级疼痛性激素水平的影响

Effect of Ultrasound-guided Lauryl Alcohol Assisted Radiofrequency Ablation on Blood Flow Classification Pain and Sex Hormone Levels in Patients with Uterine Leiomyoma

目的:探讨对经腹超声引导下进行射频消融术的子宫肌瘤患者应用聚桂醇时其血流分级、疼痛改善情况以及对机体血清性激素水平的影响。方法:选取2017年1月至2018年5月于我院接受射频消融术的58例子宫肌瘤患者,按随机数表法分成研究组(30例)和对照组(28例)。对照组子宫肌瘤患者采用经腹超声引导射频消融术予以医治;研究组即于对照组的基础再施以聚桂醇辅助消融。对比两组患者接受消融术前和治疗3个月后的血流分级、疼痛评分(VAS)及卵泡生成素(FSH)、黄体生成素(LH)、血清雌二醇(E2)三种性激素水平的改变情况。结果:两组患者接受消融术前,血流分级的分布情况、VAS评分、血清性激素含量的对比均无明显差异(P>0.05);消融术治疗3个月后,两组患者的血流分级有显著改善效果,VAS评分显著性降低、患者三种性激素分泌水平均显著降低(P<0.05),且研究组患者VAS的改善效果皆明显比对照组更好(P<0.05),而消融术后所有两组研究对象血清FSH、LH、E2的浓度相比并无明显差别(P>0.05)。结论:对子宫肌瘤患者经腹超声引导射频消融应用聚桂醇辅助治疗,患者的血流分级、疼痛缓解情况均可得到更显著的改善效果,且不影响患者性激素水平含量,推广应用价值高。

Objective:To investigate the effects of blood flow grading,pain improvement and serum sex hormone levels on uterine leiomyoma patients undergoing radiofrequency ablation guided by transabdominal ultrasound.Methods:From January 2017 to May 2018,58 patients undergoing radiofrequency ablation were divided into study group(30 cases)and control group(28 cases)by random number table method.The patients with uterine myoma in the control group were treated with radiofrequency ablation guided by transabdominal ultrasound.The changes of sex hormones in blood flow,pain score(VAS)and follicle-forming hormone(FSH),luteinizing hormone(LH)and serum estradiol(E2)were compared before and after 3 months of treatment.Results:There was no significant difference in blood flow distribution,VAS score and serum sex hormone content between the two groups before ablation(P>0.05).After 3 months of ablation,the blood flow grade of the two groups decreased significantly(P<0.05).The improvement effect of VAS was better than that of control group(P<0.05).There was no significant difference in the concentrations of FSH,LH and E2 between the two groups after ablation(P>0.05).Conclusion:For patients with uterine leiomyoma with transabdominal ultrasound guided radiofrequency ablation using polycoylenol adjuvant therapy,the blood flow grading,pain relief can be more significantly improved,and do not affect the level of sex hormone in patients,the clinical application value is high.