高流量湿化氧疗对老年肺炎患者CRP PCT的影响

Effects of High Flow Humidified Oxygen Therapy on the Expression Levels of CRP and PCT in Elderly Patients with Pneumonia

目的:比较高流量湿化氧疗与普通传统氧气疗法对老年患者肺炎的治疗效果,为高流量湿化氧疗的临床应用提供依据。方法:收集2016年10月至2019年12月本院老年病科住院治疗的下呼吸道感染老年患者80例,采用完全随机法将患者分对照组(普通传统氧气疗法)和研究组(经鼻高流量湿化氧疗,HFNC),每组40例。比较两组患者治疗前后的临床疗效及PCT、CRP、SpO2、RR、HR水平。结果:治疗前两组患者的临床症状指标及PCT、CRP、SpO2、RR、HR水平,差异无统计学意义(P>0.05)。治疗后研究组肺部啰音消失、气促消失时间及住院时间明显短于对照组,差异具有统计学意义(P<0.001);研究组PCT、CRP、HR、RR水平低于对照组,SpO2水平高于对照组,差异有统计学意义(P<0.001)。结论:应用HFNC治疗老年人肺炎的临床效果显著优于传统氧气疗法。

Objective:To compare the therapeutic effect of high flow humidified oxygen therapy and conventional oxygen therapy on pneumonia in elderly patients,and to provide basis for clinical application of high flow rate humidification oxygen therapy.Methods:80 elderly patients with pneumonia who were admitted to our hospital from October 2016 to December 2019 were selected and randomly divided into the control group and the research group according to different treatment methods.Patients in the control group were treated with transnasal continuous positive pressure ventilation therapy,and patients in the research group were treated with high-flow humidified oxygen therapy.There were 40 cases in each group.The clinical efficacy and PCT,CRP,SpO2,RR,HR levels of the two groups before and after treatment were compared.Results:The comparison of clinical symptom indexes and PCT,CRP,SpO2,RR,HR levels between the two groups before treatment revealed no statistical differences(P>0.05).After treatment,the disappearance time of pulmonary rales,shortness of breath,expectoration and the length of hospital stay were shorter than the control group(P<0.05).PCT,CRP,RR,HR level of the research group were lower,and SpO2 level was higher,than the control group,and the difference was significant(P<0.05).Conclusion:The clinical effect of HFNC in the treatment of pneumonia in the elderly is significantly better than that of traditional oxygen therapy.