热疗在胶质瘤治疗中的研究进展

Research progress on hyperthermia in the treatment of glioma

胶质瘤是很常见的恶性脑肿瘤,目前主要治疗方法包括手术、放疗与化疗,但患者生存率较低、预后较差。上述方法的一些局限性促使人们寻找更有效、更安全的治疗方法。热疗是一种局部或全身加热,利用高温杀灭肿瘤细胞,从而达到治疗效果的方法。在胶质瘤治疗中有着如创伤性小、精确性高等优点,与放化疗联用可以改善预后。目前已作为一种具有极大潜在优势的胶质瘤治疗手段。本文主要介绍应用于胶质瘤治疗的热疗方法,热疗在胶质瘤治疗中的应用前景与应用现状,以及研究相对成熟且已上市的、可应用于胶质瘤热疗的设备及操作方法。

Glioma is a highly common malignant brain tumor.Current mainstream treatments include surgery,radiotherapy and chemotherapy,but the low survival rate and poor prognosis of patients have led scientists to explore new therapies.Hyperthermia is a method of local or whole body heating that utilizes high temperature to kill tumor cells to achieve a therapeutic effect,which has multiple advantages in the treatment of glioma,such as minimal invasiveness and high precision,etc.Studies have shown that hyperthermia combined with radiotherapy and chemotherapy can improve the clinical prognosis of patients.Currently,it serves as a therapeutic tool for glioma with huge potential advantages.In this review,the hyperthermia methods applied to treat glioma were introduced.The application prospects and current status of hyperthermia in treating glioma were summarized.In addition,the mature equipment and operation methods that have been applied in the hyperthermia treatment of glioma were illustrated.