硫酸氨基葡萄糖预防舰艇官兵高强度训练致膝关节疼痛的效果

Preventive effects of glucosamine sulfate on knee joint pain of shipboard naval personnel at the circumstance of high intensity training

目的观察小剂量硫酸氨基葡萄糖预防高强度训练致膝关节疼痛的效果。方法通过招募志愿者的方式选择了268名即将参加高强度军事训练的舰艇官兵,随机分为2组,治疗组和对照组,每组134人,均为男性。治疗组使用硫酸氨基葡萄糖进行干预,对照组给予安慰剂。训练前后均使用疼痛视觉模拟量表(VAS)评分对2组官兵进行测评。结果训练前,2组官兵的VAS评分差异无统计学意义(P>0.05)。训练3个月后,官兵的VAS评分治疗组较治疗前显著改善,差异有统计学意义(P<0.05);对照组与治疗前比略有改善,差异无统计学意义(P>0.05);与对照组比较,治疗组治疗后改善更为明显,差异有统计学意义(P<0.05)。2组的药物不良反应比较,差异无统计学意义(P>0.05)。结论口服小剂量硫酸氨基葡萄糖可有效预防高强度训练导致的膝关节疼痛。

Objective To observe the effects of low dose glucosamine sulfate on the prevention of knee joint pain under high intensity training.Methods By the way of recruiting volunteers,268 shipboard naval personnel who were to take part in high intensity military training were chosen for the study and were randomly divided into the treatment group and the control group,each consisting of 134 subjects.The treatment group was intervened with glucosamine sulfate,while the control group was given placebo.Both before and after training,VAS scores of the knee joint were used to evaluate the naval personnel of the 2 groups.Results Before training,there was no statistical significance in the VAS scores,when comparisons were made between the 2 groups.Three months after training,the VAS scores of the treatment group significantly decreased,as compared with those before treatment(P<0.05),and the treatment group improved more significantly as compared with the control group(P<0.05).However,there was no statistical significance in adverse drug reactions,when comparisons were made between the 2 groups(P>0.05).Conclusion Low dose glucosamine sulfate could effectively prevent knee joint pain caused by high intensity training.