经鼻导管高流量吸氧在慢性阻塞性肺疾病加重期的应用进展

Application of high flow nasal cannula oxygen therapy in acute exacerbated COPD patients

慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)作为一种临床常见疾病,通常由于暴露在有害微粒或气体中导致肺泡通气功能障碍所致,具有持续性的呼吸系统症状、气流受限的特点,是一种可预防可治疗的疾病[1]。目前,COPD已经成为全球最严重的呼吸系统疾病之一,预计到今年将成为全球排名第三的死亡疾病。

Acute exacerbation of chronic obstructive pulmonary disease(AECOPD)is a common clinical event that can result in severe respiratory failure and substantial mortality.High-Flow through Nasal Cannula(HFNC)can deliver heated humidified air-oxygen mixture to the patients,wash out the pharyngeal dead space,generate a certain amount of positive end expiratory pressure and assure more comfort.It has been introduced in the clinical therapy in acute exacerbated COPD patients.In this paper,we reviewed the literature in recent years to assess the effect of HFNC in the treatment of AECOPD patients.