以呼吸困难为主要表现的Rosai-Dorfman病1例

A case report of Rosai-Dorfman disease with dyspnea

1病例报告患者,男,60岁,以呼吸困难9 h为主诉。晨起后无明显诱因出现呼吸困难,活动后加重,伴咳嗽,无其他症状,发病前有声嘶病史。当地医院给予抗炎及激素雾化吸入治疗,症状较前好转,建议转上一级医院,遂就诊赣南医学院第一附属医院。急诊喉部CT示:右侧声带结节;电子喉镜检查:①声门下肿物待查,②慢性咽喉炎,急诊拟"喉部肿物"收入院。

Rosai-Dorfman disease,also known as sinus histiocytosis with massive lymphadenopathy,is a kind of very rare idiopathic disease.The most common feature is the excessive accumulation of Langerhans cells in lymph nodes,but it may also occur in other areas and lead to related organ damage.We report a case of a 60-year-old man with Rosai-Dorfman disease,which led to dyspnea.Surgery is the best treatment to relieve the patient’s dyspnea in a short time.Rosai-Dorfman disease has trend to self-healing,but in the case of special location,surgery should be selected.Some similar mass recurred in the operative area and bilateral nasal cavity in half a year after operation.Now we reviewed the relevant literatures and summarized the experience of diagnosis and treatment in Rosai-Dorfman disease.