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手术联合化疗治疗以截瘫起病的复发急性早幼粒细胞白血病一例报告并文献复习

Recurrent acute promyaelocytic leukemia with paraplegic onset was treated with surgery and chemotherapy:a case report and literature review
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摘要 随着维甲酸及亚砷酸的广泛应用,急性早幼粒细胞白血病(APL)的缓解率明显提高,复发率降低,患者的生存时间明显延长,但神经系统浸润的发生率也明显上升。APL浸润致椎管肿瘤较少见,现报道我科手术联合化疗成功治疗1例APL浸润致椎管肿瘤患者。病例资料患者,女,24岁。因"确诊白血病4年,双下肢无力、麻木7 d"于2011年5月18日入院。患者2007年妊娠后期出现鼻出血、皮肤瘀斑在外院就诊,经各项检查确诊为"APL",剖宫产术后行1个疗程化疗(具体不详),此后未再继续进行治疗及中枢神经系统白血病预防。
作者 周昭贵 刘泽林 古庆利 刘焕勋 杜新 卓家才 Zhou Zhaogui;Liu Zelin;Gu Qingli;Liu Huanxun;Du Xin;Zhuo Jiacai(Huazhong University of Science and Technology Union Shenzhen Hospital(Nanshan Hospital),Shenzhen 518000,China;Shenzhen Second People’s Hospital,the First Affiliated Hospital of Shenzhen University,Shenzhen 518035,China)
出处 《中华血液学杂志》 CAS CSCD 北大核心 2020年第7期599-600,共2页 Chinese Journal of Hematology
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