老年人轻度认知功能障碍与睡眠障碍的相关性研究

The correlation between mild cognitive impairment and sleep disorders in the elderly

目的探究老年人轻度认知功能障碍(MCI)与睡眠障碍的相关性。方法纳入2018年3月至2020年4月就诊于我院的220例存在认知功能障碍的老年患者,其中单领域遗忘组65例,多领域遗忘组97例,非遗忘组58例,应用匹兹堡睡眠量表(PSQI)和日间嗜睡量表(ESS)评价患者主观睡眠情况,多导睡眠监测客观分析患者睡眠质量,分析MCI与睡眠障碍的相关性。结果 220例患者中PSQI平均得分为(17.1±3.9)分,相关性分析得出单领域遗忘组与睡眠质量、睡眠时间、日间功能障碍、PSQI总分、觉醒指数、ESS评分呈正相关(rs值分别为0.356、0.324、0.351、0.412、0.361、0.327,均P<0.05);多领域遗忘组与睡眠质量、睡眠时间、睡眠障碍评分、催眠药物评分、PSQI总分、觉醒指数、浅睡眠期、ESS评分呈正相关(rs值分别为0.283、0.323、0.346、0.401、0.379、0.412、0.228、0.251,均P<0.05),非遗忘组与睡眠时间、催眠药物评分、PSQI总分、快眼动睡眠障碍、浅睡眠期呈正相关(rs分别为0.348、0.307、0.391、0.355、0.228,均P<0.05)。结论老年MCI类型与睡眠障碍存在相关性,不同类型MCI与不同睡眠障碍因素相关性不同。

Objective To investigate the correlation between mild cognitive impairment(MCI)and sleep disorder in the elderly.Methods A total of 220 elderly patients in our hospital from March 2018 to April 2020 were enrolled in this study>including 65 single amnestic patients,97 multiple amnestic patients and 58 non-amnestic patients.The Pittsburgh Sleep Quality Index(PSQI)and Epworth sleepiness scale(ESS)were used to evaluate subjective sleep patterns.The quality of sleep were monitored and analyzed through polysomnography.The Spearman univariate correlation between MCI and sleep disorder was analyzed.Results The average PSQI score of 220 patients was(17.1±3.9)points.The Spearman univariate correlation analysis showed the following results.(l)In the single amnestic group,MCI was positively correlated with the sleep quality,sleep time,daytime dysfunction,total PSQI score,arousal index and ESS score(rs=0.356,0.324,0.351,0.412,0.361 and 0.327,respectively,all P<0.05).(2)In the multiple amnestic group,MCI was positively correlated with the sleep quality,sleep time,sleep disorder score>hypnotic drug score,total PSQI score,arousal index,light sleep period and ESS score(rs=0.283,0.323,0.346,0.401,0.379,0.412,0.228,0.251,all P<0.05).(3)In the non-amnestic group,MCI was positively correlated with the sleep time,hypnotic drug score,total score of PSQI,REM sleep disorder and light sleep period(rs=0.348,0.307,0.391,0.355 and 0.228,all P<0.05).Conclusions There are correlations between the MCI types and sleep disorders in the elderly,and different MCI types are associated with different factors on sleep disorder.