食积气滞型小儿食积咳嗽应用中药穴位贴敷联合消积止咳颗粒治疗的临床疗效探析

Clinical curative effect of TCM acupoint appl ication combined with Xiaoji Zhike grain on chi Idren with indigestion cough of food-accumulation qi-stagnation type

目的探析中药穴位敷贴联合消积止咳颗粒治疗食积气滞型食积咳嗽患儿的临床效果.方法将本院收治的80例食积气滞型食积咳嗽的患儿纳入研究样本,依据随机数字表法将其分为对照组与观察组各40例.对照组患儿给予消食止咳口服液治疗,观察组给予中药穴位敷贴与消食止咳口服液联合治疗.比较两组患儿的临床疗效,治疗前后的中医证候量表积分、血清指标变化以及不良反应发生情况.结果观察组治疗总有效率远高于对照组(P<0.05);经治疗后,观察组患者的中医证候量表积分显著低于对照组(P<0.05);观察组患者的血清白细胞介素6(IL-6)较对照组显著降低(P<0.05),其血清白细胞介素10(IL-10)较对照组显著升高(P<0.05),其嗜酸性粒细胞(EOS)比值较对照组显著降低(P<0.05);患者均没有出现明显不良反应.结论给予食积气滞型食积咳嗽患儿以中药穴位敷贴联合消积止咳颗粒治疗,患儿病情改善明显,且安全可靠.

0bjective To explore clinical curative ffct of traditional Chinese medicine(TCM)acupoint application combined with Xiaoji Zhike grain on children with indigestion cough of food-accumulation qi-stagnation type.Methods A total of 80 children with indigestion cough of food-accumulation qi-stagnation type who were admitted to the hospital from October 2018 to October 2019 were included in study samples.They were divided into control group and observation group by random number table method,40 cases in each group.The control group was treated with Xiaoshi Zhike grain,while observation group was treated with TCM acupoint application combined with Xiaoshi Zhike grain.The clinical curative effect,changes in scores of TCM syndromes and serum indexes before and after treatment,and occurrence of adverse reactions were compared between the Iwo groups.Results The total response rate of treatment in observation group was much higher than that in control group(P<0.05).After treatment,scores of TCM sy ndromes in observation group were significantly lower than those in control group(P<0.05).The serum interleukin 6(IL-6)in observation group was significantly lower than that in control group(P<0.05),serum interleukin 10(IL-10)was significantly higher than that in control group(P<0.05),eosinophil(EOS)ratio was significantly lower than that in control group(P<0.05).There were no significant adverse reactions in any patients.Conclusion After application of TCM acupoint application combined with Xiaoshi Zhike grain in children with indigestion cough of food-accumulation qi-stagnation type,their conditions are significanly improved.It is safe and reliable.