双腔频率适应性起搏器对SSS患者的效果及对心功能、生活质量的影响

The Effect of Dual-chamber Frequency-adaptive Pacemaker on SSS Patients and Its Influence on Cardiac Function and Quality of Life

目的对病态窦房结综合征(SSS)患者采用双腔频率适应性起搏器,分析治疗效果及其对患者心功能、生活质量的影响。方法选取2015年1月~2019年1月我院收治的诊断为病态窦房结综合征的患者108例,随机分为对照组(54例)和观察组(54例),对照组采用双腔非频率适应性起搏器治疗,观察组采用双腔频率适应性起搏器治疗,比较两组治疗效果、治疗后6个月心功能指标及生活质量评分。结果观察组的治疗总有效率为92.59%,高于对照组的83.33%,差异有统计学意义(P<0.05);两组治疗前后左房舒张末期内径(LAEDD)、左室舒张末期内径(LVEDD)比较,差异无统计学意义(P>0.05);观察组治疗后6个月6分钟步行实验(6-MWT)、左室射血分数(LVEF)水平均高于治疗前,脑钠肽(BNP)水平低于治疗前,且观察组改善情况优于对照组,差异有统计学意义(P<0.05)。两组治疗后生活质量各维度评分均高于治疗前,且观察组高于对照组,差异有统计学意义(P<0.05)。结论在病态窦房结综合征患者中采用双腔频率适应性起搏器治疗的疗效确切,且能有效改善患者的心功能指标及生活质量。

Objective To use a dual-chamber frequency-adaptive pacemaker for patients with sick sinus syndrome(SSS)to analyze the effect of treatment and its influence on patients'cardiac function and quality of life.Methods A total of 108 patients with sick sinus syndrome diagnosed in our hospital from January 2015 to January 2019 were selected and randomly divided into a control group(54 cases)and an observation group(54 cases).The control group was double-chambered For non-frequency adaptive pacemaker treatment,the observation group was treated with a dual-chamber frequency adaptive pacemaker.The treatment effects,cardiac function indexes and quality of life scores 6 months after treatment were compared between the two groups.Results The total effective rate of treatment in the observation group was 92.59%,which was higher than 83.33% in the control group,the difference was statistically significant(P<0.05);There was no significant difference in the left atrium end diastolic diameter(LAEDD)and left ventricular end diastolic diameter(LVEDD)between the two groups before and after treatment(P>0.05);the observation group 6-minute walk test(6-MWT)6 months after treatment,Left ventricular ejection fraction(LVEF)and levels were higher than before treatment,brain natriuretic peptide(BNP)levels were lower than before treatment,and the improvement of the observation group was better than that of the control group,the difference was statistically significant(P<0.05).The scores of all dimensions of the quality of life after treatment in the two groups were higher than before treatment,and the observation group was higher than the control group,the difference was statistically significant(P<0.05).Conclusion The use of dual-chamber frequency-adaptive pacemaker therapy in patients with sick sinus syndrome has a definite effect and can effectively improve the patients'cardiac function and quality of life.