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145例医院获得性肺炎患者下呼吸道分泌物细菌培养、菌种鉴定及耐药情况研究

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摘要 目的研究医院获得性肺炎患者下呼吸道分泌物细菌培养、菌种鉴定及耐药情况。方法选取我院2018年6月~2019年6月收治的医院获得性肺炎患者145例作为研究对象,均行下呼吸道分泌物细菌培养、菌种鉴定,并经药敏试验分析其耐药情况。结果经细菌培养、菌种鉴定,145例医院获得性肺炎患者中,共检出197株菌株。其中鲍曼不动杆菌28.93%(57/197)、铜绿假单胞菌23.35%(46/197)、肺炎克雷伯菌检出率22.84%(45/197)高于肺炎链球菌、大肠埃希菌、金黄色葡萄球菌、嗜麦芽窄食单胞菌及其他菌种(P<0.05)。耐药情况:鲍曼不动杆菌仅对米诺环素、多粘菌素B敏感性较高,对其他抗菌药物耐药性均较高;肺炎克雷伯菌对氨苄西林、头孢他啶/棒酸、头孢噻肟耐药率较高;铜绿假单胞菌对左氧氟沙星、诺氟沙星、环丙沙星产生耐药,对其他抗菌药物无耐药性。结论医院获得性肺炎患者下呼吸道分泌物中细菌种类繁多,以鲍曼不动杆菌、铜绿假单胞菌、肺炎克雷伯菌为主,临床应针对其耐药性、敏感性选择合理抗菌药物治疗,提升治疗效果。
作者 程环
出处 《现代诊断与治疗》 CAS 2020年第11期1774-1776,共3页 Modern Diagnosis and Treatment
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