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中医临床疗效个体化评价应用混合方法研究设计思路 被引量:13

Application of mixed methods research in individualized therapeutic evaluation of clinical trials of traditional Chinese medicine
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摘要 中医临床实践以辨证论治和整体观为特色,而定量评价为主的传统随机对照试验难以反映中医个体化疗效和整体调节作用。单病例随机对照试验的设计为定量评价中医临床个体化疗效带来契机;应用混合方法研究,采用探索性序列设计、解释性序列设计或聚敛式设计可从不同方面为中医临床疗效个体化评价提供丰富数据,使中医的整体观和人文特征在个体研究层面得到丰富的体现。 The characteristics of traditional Chinese medicine(TCM)practice include treatment based on syndrome differentiation and holism,which determines it is difficult to reflect the individualized therapeutic evaluation and overall regulation of TCM through traditional randomized controlled trials,which is based on quantitative evaluation.The implementation of N-of-1 trials will provide opportunities for quantitative evaluation of individualized therapeutic evaluation of TCM.Using mixed methods research,such as exploratory sequence design,interpretive sequence design or convergent design can provide abundant data to individualized therapeutic evaluation of TCM in different aspects,which may reflect holism and humanities characteristics of TCM in individual level.
作者 邱瑞瑾 赵晨 钟长鸣 胡嘉元 李敏 黄涯 韩松洁 何天麦 关曼柯 陈静 商洪才 QIU Ruijin;ZHAO Chen;ZHONG Changming;HU Jiayuan;LI Min;HUANG Ya;HAN Songjie;HETianmai;GUAN Manke;CHEN Jing;SHANG Hongcai(Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing,Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100700,P.R.China;Institute of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences,Beijing 100700,P.R.China;Beijing University of Chinese Medicine Third Affiliated Hospital,Beijing 100029,P.R.China;Baokang Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin 300193,P.R.China)
出处 《中国循证医学杂志》 CSCD 北大核心 2020年第8期973-978,共6页 Chinese Journal of Evidence-based Medicine
基金 国家自然科学基金项目(编号:81904051) 中央高校基本科研业务费专项(编号:2019-JYB-JS-033)。
关键词 中医学 疗效评价 个体化 混合方法研究 Traditional Chinese medicine Therapeutic evaluation Individualization Mixed methods research
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