祛痰散热汤联合经皮理疗治疗小儿支气管肺炎临床疗效及对炎症因子水平的影响

Clinical Efficacy of Using Qutan Sanre Decoction Combined with Percutaneous Physiotherapy in the Treatment of Children with Bronchial Pneumonia and Its Effect on Inflammatory Factor

目的:观察祛痰散热汤联合经皮理疗对小儿支气管肺炎的临床疗效、对炎症因子水平的影响。方法:临床选取104例符合支气肺炎诊断标准的患儿,均为我院2016年12月~2018年12月住院患儿,采用随机数字表法将患儿分为两组,两组患儿均给予常规基础治疗,对照组患儿给予经皮理疗,治疗组患儿给予祛痰散热汤联合经皮理疗。比较两组患儿总疗效,治疗前后症状总积分变化,症状及体征(发热、咳嗽、气促、异常呼吸音)消失时间,治疗前后炎症因子白介素-6(IL-6)、感染指标降钙素原(PCT)、C反应蛋白(CRP)水平变化、治疗前后两组患儿血常规检查结果(白细胞计数、中性粒细胞水平),以及不良反应情况。结果:观察组患儿总有效率(98.08%),高于对照组(90.38%),P<0.05;治疗前,两组患儿发热、咳嗽、气促、痰鸣等症状总积分,IL-6、PCT、CRP等化验室指标水平相当,P>0.05,治疗后各组患儿症状总积分、化验室指标较前改善,观察组患儿治疗后症状总积分、血性炎症因子水平优于对照组,P<0.05;观察组患儿治疗后发热、咳嗽、气促、异常呼吸音等症状、体征消失时间均低于对照组,白细胞计数、中性粒细胞水平指标优于对照组,P<0.05,观察组患儿不良反应率(13.46%)略高于对照组(7.69%),但两组数据无统计学差异,P>0.05。结论:祛痰散热汤联合经皮理疗治疗小儿支气管肺炎临床疗效显著,患儿症状及体征改善,恢复快,安全性良好,值得推广和应用。

Objective:To inestigate the clinical efficacy of Qutan Sanre Decoction combined with percutaneous physiotherapy on children with bronchial pneumonia and the effect on inflammatory factor levels.Methods:104children with bronchial pneumonia were selected clinically from December 2016to December 2018in our hospital.The children were divided into two groups using the random number table method.Patients in the controlled group were treated with percutaneous physiotherapy,while the treatment group were treated with Qutan Sanre Decoction combined with percutaneous physiotherapy.Compared the total curative effect of the two groups of children,the change of the total score of symptoms before and after treatment,the disappearance time of symptoms and signs(fever,cough,shortness of breath,abnormal breathing sounds),the inflammation factor interleukin-6(IL-6),and the infection index changes in protamine(PCT)and C-reactive protein(CRP)levels,blood test results(white blood cell counts,neutrophil levels),and adverse reactions in the two groups of children before and after treatment.Results:The total effective rate of children in the observation group(98.08%)was higher than that in the controlled group(90.38%),P<0.05.Before treatment,the total scores of fever,cough,shortness of breath,sputum and other symptoms in the two groups of children,IL-6,PCT,CRP and other laboratory indicators were equivalent,P>0.05,after treatment,the total symptoms and laboratory indicators of children in each group improved compared with before,the observation group of children after treatment of total symptoms and blood inflammatory factor levels were better than the controlled group,P<0.05.Children in the observation group had lower fever,cough,shortness of breath,abnormal breathing sounds,and other signs and symptoms than the controlled group.Leukocyte count and neutrophil level were better than those in the controlled group,P<0.05,the adverse reaction rate of children in the observation group(13.46%)was slightly higher than that in the controlled group(7.69%),but there was no statistical difference between the two groups,P>0.05.Conclusion:Qutan Sanre Decoction combined with percutaneous physiotherapy has obvious clinical effect in treating children with bronchial pneumonia.The symptoms and signs of children are improved,the recovery is fast,the safety is good,and it is worth popularizing and applying.