膦甲酸钠氯化钠治疗人乳头状瘤病毒感染宫颈炎的临床分析

Clinical analysis of sodium phosphonoformate and sodium chloride in the treatment of cervicitis infected with human papillomavirus

目的探究膦甲酸钠氯化钠治疗人乳头状瘤病毒感染宫颈炎的临床分析。方法选取2017年1月至2019年3月本院收治的116例人乳头状瘤病毒感染宫颈炎患者作为研究对象,按照随机数表法分为对照组(n=58,重组人干扰素α-2b栓治疗)和观察组(n=58,膦甲酸钠氯化钠治疗),比较两组患者临床治疗效果以及宫颈炎指标评分。结果治疗后,观察组患者临床治疗有效率为94.83%,明显高于对照组的74.14%(P<0.05)。观察组患者宫颈炎指标评分为(2.18±0.98)分,明显低于对照组的(6.41±1.27)分(P<0.05)。观察组患者人乳头状瘤病毒转阴率为98.28%,明显高于对照组的60.34%(P<0.05)。结论采用膦甲酸钠氯化钠治疗人乳头状瘤病毒感染宫颈炎患者,能够提高患者的治疗效果,降低患者炎症严重程度,值得临床运用及推广。

Objective To study the effect of sodium salt sodium chloride on the treatment of human papillomavirus infection in cervicitis.Methods 116 cases of HPV-infected cervicitis in our hospital were enrolled from January 2017 to March 2019,they were divided into control group(n=58,recombinant human interferon-2b-suppository)and observation group(n=58,sodium-sodium formate and sodium chloride)according to the random number table method,and the clinical treatment and cervicitis index scores of the two groups were compared.Results After treatment,the effective rate of clinical treatment in the observation group was 94.83%,significantly higher than 74.14%in the control group(P<0.05).The score of cervicitis index in the observation group was(2.18±0.98)scores significantly lower than that in the control group(6.41±1.27)scores(P<0.05).The negative rate of HPV in the observation group was 98.28%,significantly higher than that in the control group(60.34%)(P<0.05).Conclusion The treatment of cervicitis with human papilloma virus infection can improve the treatment effect of the patients,reduce the severity of the patient's inflammation,and it is worth of clinical application and the clinical popularization.