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低分子肝素联合充气加压装置预防子宫内膜癌术后下肢深静脉血栓 被引量:11

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摘要 目的探讨低分子肝素联合周期性充气加压装置预防腹腔镜子宫内膜癌术后下肢深静脉血栓形成的临床应用价值。方法选取2017年1月至2019年1月于河北省秦皇岛市第一医院因具有血栓中高危因素的子宫内膜癌Ⅰ期住院120例患者为研究对象,所有患者均行腹腔镜手术,根据随机数表法分为三组,每组40例。其中联合组应用低分子肝素钙和周期性充气加压装置,单用低分子肝素钙组应用低分子肝素钙,单用周期性充气加压装置组应用周期性充气加压装置。各组患者均记录术后第7天凝血指标,并统计下肢深静脉血栓发生率。结果①术后第7天,单用周期性充气加压装置组下肢深静脉血栓发生率(17.5%)显著高于联合组(2.5%)和单用低分子肝素钙组(15.0%),差异有显著性(P<0.05);②联合组D-二聚体、血浆纤维蛋白原值明显低于其他两组,差异有显著性(P<0.05);③三组凝血酶原时间、活化部分凝血活酶时间比较,差异均无显著性(P>0.05)。结论低分子肝素联合周期性充气加压装置可明显降低腹腔镜下子宫内膜癌术后下肢深静脉血栓的发生率,具有临床指导意义。
出处 《中国临床医生杂志》 2020年第9期1099-1101,共3页 Chinese Journal For Clinicians
基金 河北省秦皇岛市科技攻关项目(201805A082)。
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