基于数据场与3-D图形表示的DNA序列分析

DNA Sequence Analysis Based on Data Field and 3-D Graphical Representation

该文提出了DNA序列的一种3-D图形表示,并且针对此图形表示的非退化性给出了数学证明。然后计算所提3维图形表示的L/L矩阵的ALE指标,并给出了所提3维图形的图半径,从而对DNA序列进行数值刻画。结合物理学中重力场势函数的思想,构造了向量形式的数据对象间的势函数,进而以K-近邻算法为分类器,对208个RIG-I基因进行了分类识别。实验结果证明了该文所提的分类办法是有效的。

This paper presents a 3-D graphical representation of the DNA sequence,and gives a mathematical proof for the non-degenerate nature of the graphical representation.Then calculate the ALE index of the L/L matrix represented by the proposed 3-dimensional graph,and give the graph radius of the proposed 3-dimensional graph,thereby numerically characterizing the DNA sequence.Combining the idea of the potential function of gravity field in physics,the potential function between data objects in the form of vectors is constructed,and then 208 RIG-I genes are classified and identified using the K-nearest neighbor algorithm as the classifier.The experimental results prove that the classification method proposed in this paper is effective.