以多发性皮下结节为首发症状的肾细胞癌一例报告

A case report of renal cell carcinoma with initial symptom of multiple subcutaneous nodules

肾癌发生皮肤转移者少见,而以多发性皮下结节为首发症状的更罕见。2018年1月19日无锡市第二人民医院收治1例以多发性皮下结节为首发症状的肾细胞癌患者,因患者右肾癌分期为cT4N2M1、Ⅳ期,无手术指征,以内科治疗为主。为明确肿瘤类型,局麻下行右腹部皮下单个结节活检术,术中快速冰冻病理检查确诊为肾透明细胞癌。活检术后5 d开始口服舒尼替尼治疗,活检术后7个月因脑多发转移死亡,总生存期7个月。

Cutaneous metastasis of renal cell carcinoma(RCC)is rare.Particularly,it is even more rare that multiple subcutaneous nodules become the first symptom of RCC.On January 19,2018,a RCC patient with first symptom of multiple subcutaneous nodules was admitted to Wuxi No.2 People’s Hospital.The patient's right renal cancer stage was cT4N2M1,stageⅣ.He has no surgical indication and medical treatment was the main strategy.Sunitinib was administered orally five days after the biopsy.He died of multiple brain metastases seven months after the operation.The overall survival was 7 months.