超声诊断在孕妇胎儿十二指肠闭锁的预测价值

Predictive value of ultrasound in fetal duodenal atresia of pregnant women

目的探究超声检测在孕妇胎儿十二指肠闭锁中的预测价值。方法回顾性分析2 819例晚孕产妇的检查结果,对其超声检查结果进行分析,对其中发现的76例十二指肠闭锁并行引产胎儿尸体进行解剖分析,设为观察组,同时选择另80例正常胎儿做对照组,对2组胎儿超声影像检查结果进行对比分析,并探究超声检测在预测十二指肠闭锁中的价值。结果超声检测76例观察组胎儿合并十二指肠闭锁,尸体解剖发现其中74例为十二指肠闭锁,1例为空回肠闭锁,1例为肛门闭锁,双泡征出现率100.00%(76/76),诊断准确率为97.37%(74/76),对照组胎儿双泡征出现率为1.25%(1/76),2组对比差异具有统计学意义(P<0.05);观察组76例胎儿中合并羊水过多者有68例(89.47%),对照组胎儿中合并羊水过多者有3例(3.75%),2组对比差异具有统计学意义(P<0.05);检查发现76例观察组胎儿中有11例合并其他结构异常,分别为3例先天性心脏病,3例多囊肾,1例足内翻,4例唇腭裂。结论超声诊断在孕妇胎儿十二指肠闭锁检查中具有较好的预测价值,能够较好的与正常胎儿进行区分,同时大部分十二指肠闭锁胎儿合并羊水过多,可作为临床检查参考指征。

Objective To explore the predictive value of ultrasound in fetal duodenal lockup in pregnant women.Methods The results of 2 819 late pregnant women were retrospectively analyzed.Among them,76 cases of duodenal atresia and induced fetal cadavers were dissected and analyzed.The experimental group was set up and the other 80 normal fetuses were chosen as the control group.The results of sonographic examination of the two groups were compared and analyzed,and the value of ultrasonic examination in predicting duodenal atresia was explored.Results A total of 76 cases of fetus complicated with duodenal closure in the experimental group were examined by ultrasound.There were 74 cases of duodenal atresia,1 case of empty ileum atresia and 1 case of anal atresia.The occurrence rate of double vesicle sign was 100.00% (76/76),and the diagnostic accuracy was 97.37% (74/76).In the control group,the occurrence rate of double bubble sign was 1.25% (1/76),and there was significant difference between the two groups (P<0.05).Among 76 fetuses in the experimental group,68 cases (89.47%) were complicated with oligohydramnios,and 3 cases (3.75%) in the control group.There was significant difference between the two groups (P<0.05).The examination showed that 11 of 76 fetuses in the experimental group were complicated with other structural abnormalities,including 3 congenital heart disease,3 polycystic kidney,1 foot varus and 4 cleft lip and palate.Conclusion Ultrasound diagnosis has a good predictive value in fetal duodenal atresia examination of pregnant women,and can be distinguished from normal fetus.At the same time,most of duodenal atresia fetuses with amniotic fluid excess.It can be used as a reference for clinical examination.