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斜外侧腰椎椎间融合术治疗退行性腰椎管狭窄60例 被引量:4

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摘要 目的:探讨斜外侧腰椎椎间融合术(OLIF)治疗退行性腰椎管狭窄的近期效果及对患者血清TNF-α,IL-6,CRP水平的影响。方法:选择本院2017年7月至2018年6月间收治的60例退行性腰椎管狭窄患者临床资料为对象,分析OLIF对退行性腰椎管狭窄的治疗效果及术后3个月、6个月VAS评分、ODI指数、SF-36评分,血清TNF-α,IL-6,CRP水平变化情况。结果:所有患者均获得6个月随访,CT评估结果显示患者左、右两侧椎间孔间隙高度较术前均显著增高,左、右两侧椎间孔面积较术前均显著增大,差异有统计学意义(P<0.001);MRI评估结果显示患者椎管内径大小、盘黄间隙高度较术前均显著升高,椎管面积较术前显著增大,差异有统计学意义(P<0.001);术后3个月及6个月末次随访,患者腰痛VAS评分、腿痛VAS评分、ODI指数,血清TNF-α,IL-6,CRP水平相较于术前均显著降低,差异有统计学意义(P<0.001),术后3个月及6个月末次随访SF-36评分相较于术前均显著升高,差异有统计学意义(P<0.001);术后仅出现下肢麻木2例(3.33%),屈髋乏力1例(1.67%);术后1个月出现融合器向下位移导致的腰痛1例(1.67%)。结论:斜外侧腰椎椎间融合术可显著改善退行性腰椎管狭窄患者椎管内空间结构及术后腰腿疼痛程度,减轻腰椎功能障碍,提高生活质量,且术后并发症少,近期疗效满意。
出处 《中国中医骨伤科杂志》 CAS 2020年第8期80-83,88,共5页 Chinese Journal of Traditional Medical Traumatology & Orthopedics
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  • 1潘力,李忠华,马廉亭,余泽,陈刚.椎管内静脉丛的应用解剖学研究[J].中国临床神经外科杂志,2006,11(11):664-666. 被引量:18
  • 2于杰,朱立国,高景华,王尚全.腰椎间盘突出症患者血清白细胞介素1β、白细胞介素6、肿瘤坏死因子α表达与其疼痛的相关性[J].中国组织工程研究与临床康复,2007,11(2):301-304. 被引量:55
  • 3Smith M,Davis MA,Stano M. Aging baby boomers and the rising cost of chronic back pain:Secular trend analysis of longitudinal Medical Expenditures Panel Survey data for years 2000 to 2007[J].JOURNAL OF MANIPULATIVE AND PHYSIOLOGICAL THERAPEUTICS,2013,(01):2-11.
  • 4Wil iam CW,Jamie B,Thomas JG. Degenerative lumbar spinal stenosis:an evidence-based clinical guide line for the diagnosis and treatment of degenerative lumbar spinal stenosis[J].SPINE,2008.305-310.
  • 5Kaymaz M,Borcek AO,Emmez H. Effectiveness of single posterior decompressive laminectomy in symptomatic lumbar spinal stenosis:a retrospective study[J].Turk Neurosurg,2012,(04):430-434.
  • 6Son S,Kim WK,Lee SG. A comparison of the clinical outcomes of decompression alone and fusion in elderly patients with two-level or more lumbar spinal stenosis[J].J Korean Neurosurg Soc,2013,(01):19-25.
  • 7Nakamura T,Okada T,Endo M. Angiopoietin-like protein 2 induced by mechanical stress accelerates degeneration and hypertrophy of the ligamentum flavum in lumbar spinal canal stenosis[J].PLoS One,2014,(01):e85542.
  • 8Takahashi N,Kikuchi S,Shubayev VI. TNF-alpha and phosphorylation of ERK in DRG and spinal cord:insights into mechanisms of sciatica[J].SPINE,2006,(05):523-529.
  • 9Ozaktay AC,Kal akuri S,Takebayashi T. Effects of interleukin-1 beta,interleukin-6,and tumor necrosis factor on sensitivity of dorsal root ganglion and peripheral receptive fields in rats[J].European Spine Journal,2006,(10):1529-1537.
  • 10Gronbald M,Virri J,Tolonen J. A Control ed immunohistochemical study of inflammatory cells in disc herniation tissue[J].SPINE,1994.2744.

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