刺激响应性聚合物微球的制备、性能及应用

Fabrications,Properties,and Applications of Stimuli-Responsive Polymer Microspheres

作为典型的软物质材料,聚合物微球因其独特的微尺度、扩散性、渗透性及可修饰性而广泛应用于催化、药物传输、生物传感、微反应器、化学分离以及涂层材料等领域。为满足苛刻应用环境对微球的性能要求,相继出现了各类环境响应性聚合物微球。针对近年来刺激响应性微球的研究进展,本文综述了聚合物响应性微球的制备策略及形貌,以及对温度、pH、磁场、离子强度、光和CO2敏感的响应性聚合物微球体系;并讨论了不同类型刺激响应微球的响应机理及应用,分析了其存在的不足,展望了其应用前景和发展方向。

Polymer microspheres are considered to be the typical soft materials which are widely used in catalysis,drug delivery,biosensing,microreactors,chemical separation and coating fields because of their unique properties,such as the micro-scale,diffusion,penetration and ease of modification.In order to meet the requirement for use in hostile environments,stimuli-responsive microspheres whose properties significantly change in response to the minor variation of environmental conditions have been developed.This paper reviews the diverse fabrication strategies and morphologies of the responsive polymer microspheres which are sensitive to temperature,pH,magnetic field,ionic strength,light and CO2 stimulus,respectively.The relevant stimuli-response mechanisms,applications and the demerits of the responsive microspheres are summarized and discussed,then the potential applications and future prospects of the sensitive microspheres are also analyzed.