冠状病毒疫苗的研究进展

Recent advances in the vaccine development against coronavirus

严重急性呼吸综合征冠状病毒2(severe acute respiratory syndrome coronavirus 2,SARS-CoV-2)自被发现以来就引起了人们的广泛关注,开发针对该病毒的安全、有效疫苗成为近期的研究热点。本文以高致病性冠状病毒疫苗(包括灭活疫苗、重组亚单位疫苗、重组病毒载体疫苗和核酸疫苗)的研究展开综述,为研制SARS-CoV-2疫苗提供参考。

Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has attracted attention worldwide.The development of safe and effective vaccines against this virus has become an urgent need.This article reviews the research on coronavirus vaccines,including inactivated vaccines,genetically engineered recombinant subunit vaccines,nucleic acid vaccines,and viral vector-based vaccines.