摘要
近年来,随着冠心病发病率不断升高,该病已成为国人健康的重大威胁。研究表明转化生长因子-β(transforming growth factor-β,TGF-β)在冠心病的发生发展中起着至关重要的作用,它主要调节细胞生长、促进组织纤维化、抑制炎症等,且诸多治疗冠心病的药物均与TGF-β有关。本文综述了近年来TGF-β与冠心病及其治疗药物(包括西药及中药)之间的关系,为中西医工作者对治疗及研究该病提供一定的参考及依据。
In recent years, coronary heart disease has become a significant threat to the health of Chinese people with its continuously increasing incidence rate. Research has shown that transforming growth factor-β(TGF-β)plays a crucial role in the development and progression of coronary heart disease. It mainly regulates cell growth, promotes tissue fibrosis, and inhibits inflammation. In addition, a large number of drugs for the treatment of coronary heart disease are related to TGF-β. This article reviews the relationship between TGF-β and coronary heart disease as well as its therapeutic drugs(including Western medicine and traditional Chinese medicine) in recent years, and provides a reference and basis for traditional Chinese and Western medical workers to treat and study this disease.
作者
毛琳慎(综述)
杨思进(审校)
MAO Linshen;YANG Sijin(Department of Cardiovascular Disease,the Affiliated T.C.M Hospital of Southwest Medical University,Luzhou 646000,Sichuan Province,China)
出处
《西南医科大学学报》
2020年第4期411-415,共5页
Journal of Southwest Medical University
基金
四川省科技厅项目(2018SZ0060)。
关键词
冠心病
TGF-Β
药物
综述
Coronary artery disease
TGF-β
Medicine
Review