牛肝菌粗多糖抗运动病作用的原理研究

Study on the Mechanism of Crude Polysaccharide of Boletus spp. Against Motion Sickness

为研究牛肝菌粗多糖抗运动病作用原理,以小鼠为对象建立眩晕模型进行分组试验。迷宫和跳台试验均表明,给予机械旋转导致眩晕的小鼠灌胃牛肝菌粗多糖后,能够有效降低小鼠眩晕程度,灌胃剂量与抑制眩晕的效果有一定的正比例关系,血清中的5-羟色胺含量显著降低。牛肝菌粗多糖对运动病的防治有一定的效果。

In order to study the mechanism of action of crude polysaccharide of Boletus spp. on motion sickness. The mice were used to establish vertigo model for grouping test. Maze test and platform jumping test showed that the mice with vertigo caused by mechanical rotation could effectively reduce the degree of vertigo by gavage of crude polysaccharide of Boletus spp.. The dosage of gavage was positively related to the effect of vertigo inhibition, and the content of 5-HT in serum was significantly reduced. The crude polysaccharide of Boletus sp. has a certain effect on the prevention and treatment of sports diseases.