布鲁菌病骨关节炎的表现与治疗研究进展

Research progress in manifestations and treatments of brucellosis osteoarthritis

布鲁菌病(brucellosis)是一种常见的由布鲁菌导致的全球性人畜共患疾病,其临床表现多种多样,部分患者表现出发热、出汗和骨骼肌肉疼痛等症状。布鲁菌病最常见的并发症是骨关节炎,包括脊柱炎、骶髂关节炎,以及骨髓炎、滑囊炎、腱鞘炎等外周关节炎。脊柱和骶髂关节是布鲁菌病骨节关炎最常见的受累部位,而骨髓炎、滑囊炎和腱鞘炎等外周关节炎的病症报道较少。早期正确的治疗对布鲁菌病骨关节炎患者至关重要,药物治疗和手术治疗是当前布鲁菌病骨关节炎治疗的2种手段。文中通过阐述布鲁菌病骨关节炎的临床表现及治疗,以期帮助临床医师加深对布鲁菌病的认识。

Brucellosis is a common global zoonotic disease caused by Brucella,which has a variety of clinical manifestations.Fever,sweating and musculoskeletal pains appear in partial brucellosis patients.The most common complication of brucellosis is osteoarthritis,including spondylitis,sacroiliitis,and peripheral arthritis such as osteomyelitis,bursitis,and tenosynovitis.The spine and sacroiliac are the most frequent affected sites of brucellosis osteoarthritis;however,the reports of peripheral arthritis such as osteomyelitis,bursitis,and tenosynovitis are low.Early and proper treatment is vital for patients with brucellosis osteoarthritis.The therapy of drugs and surgery are two current options for treatment of brucellosis osteoarthritis.In this review,clinical manifestations and treatments of brucellosis osteoarthritis are discussed in detail,which are helpful to deepen clinicians'knowledge in brucellosis.