儿童Kaposi水痘样疹56例临床分析

Clinical Analysis of 56 Cases of Children Kaposi’s Varicelliform Eruption

目的探讨儿童Kaposi水痘样疹(KVE)的临床特征、合理治疗及转归。方法对本院收治的56例KVE患儿的临床资料进行回顾性分析。结果56例KVE患儿多伴有基础皮肤病史,以湿疹、特应性皮炎(AD)居多(94.64%);有单纯疱疹患者接触史14例(25%)。患儿均有典型临床表现,经有效治疗3~16(8.88)d痊愈出院。结论KVE多发生于有湿疹、AD病史的婴幼儿。早期采用足量有效的抗病毒药是治疗成功的关键,联合用药有利于及时控制KVE急性期的病情。

Objective In order to investigate the clinical features,diagnosis and appropriate treatment of Kaposi’s varicelliform eruption(KVE)in children.Methods A retrospective analysis of clinical data on 56 cases of KVE in children was conducted.Results Almost all patients had primarily skin lesions before KVE,mostly atopic dermatitis(AD)and eczema(94.64%).Fourteen(25%)children had the history of contact with herpes simplex patient.They all had typical clinical manifestations and recovered after 3 to 16(8.88)days of treatment.Conclusion KVE mostly occurs in children with eczema and AD.Early application of adequate and effective intravenous antiviral medication is the key to successful treatment.The therapeutic effects of combination with intravenous immunoglobulin are significantly better in the management of acute stage.