Omega-3脂肪酸预防和治疗多囊卵巢综合征并发症的研究进展

Advances in the Prevention and Treatment of PCOS Complications by Omega-3 Fatty Acids

多囊卵巢综合征(PCOS)被认为是最常见的女性内分泌疾病之一,除疾病本身引起的生殖功能异常外,PCOS引起的代谢紊乱及相关并发症也是影响患者生存质量的重要因素。目前的研究结果表明,虽然omega-3脂肪酸是缓解PCOS相关并发症的有效药物之一,但在饮食中如何使用omega-3脂肪酸对PCOS患者的并发症进行系统性控制仍待进一步研究。现主要综述omega-3脂肪酸对PCOS患者体质量指数(BMI)、胰岛素抵抗程度、异常炎症因子表达水平及对甾体激素水平的影响,总结omega-3脂肪酸治疗PCOS并发症的临床疗效的研究进展。

Polycystic ovary syndrome(PCOS)is considered to be one of the most common female endocrine diseases.In addition to the abnormal reproductive function caused by this disease,the metabolic disorders and related complications caused by PCOS are also important factors affecting the quality of life of PCOS patients.Current research results indicate that although omega-3 fatty acids are one of the effective drugs to alleviate PCOS-related complications,how to use omega-3 fatty acids in the diet to systematically control the complications in PCOS patients still needs further research.This paper reviews the effects of omega-3 fatty acids on BMI,insulin resistance index,abnormal inflammatory factors and steroid hormone levels in PCOS patients.We summarize the results of clinical efficacy on the treatment of PCOS complications with omega-3 fatty acids.