Expression of HLA-DP in patients with neuromyelitis optica spectrum disorders

Objective To investigate the effect of HLA-DP gene expression on the susceptibility and disease status of neuromyelitis optica spectrum disorders(NMOSD).Methods A total of 86 NMOSD patients(52 in acute phase and 34 in remission phase),52 multiple sclerosis(MS)patients(20 in acute phase and 32 in remission phase)diagnosed in Department of Neurology,the Third Affiliated Hospital of Sun Yat・sen University and 29 healthy controls were enrolled prospectively.