Long-term effects of GnRHa on central precocious puberty or early and fast puberty children

Objective To investigate the long-term effects of GnRHa treatment on final height gain,gonadal function,and body mass index(BMI)in children with central precocious puberty(CPP)or early and fast puberty(EFP),and to explore the influencing factors of height gain and early predictors.Methods Fifty patients with CPP and 44 patients with EFP who were treated with GnRHa for more than 2 years were enrolled(80 females and 14 males).