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瞬时受体电位香草素受体4与骨关节炎关系的研究进展 被引量:2

Advancement of research on the relationship between transient receptor potential vanilloid 4 and osteoarthritis
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摘要 瞬时受体电位香草素受体4(transient receptor potential vanilloid4,TRPV4)是一种非选择性阳离子通道蛋白,在多种组织中均有表达。研究表明TRPV4介导骨关节炎(osteoarthritis,OA)相关的多条信号通路,与OA的进展关系密切。本文从TRPV4的生理功能、TRPV4在OA进展中的作用机制、TRPV4在OA治疗中的作用3个方面,对TRPV4与OA关系的研究进展进行了综述。
作者 沈雪 张琥 薛艳 陈龑 龚幼波 蒋鼎 曹月龙 SHEN Xue;ZHANG Hu;XUE Yan;CHEN Yan;GONG Youbo;JIANG Ding;CAO Yuelong
出处 《中医正骨》 2020年第8期30-33,共4页 The Journal of Traditional Chinese Orthopedics and Traumatology
基金 国家自然科学基金项目(81373665,81973874)。
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