过渡金属催化的不对称芳基-芳基偶联反应:轴手性联芳基化合物的合成研究进展

Research Progress on Synthesis of Axially Chiral Biaryl Derivatives via Transition-metals Catalyzed Aryl-Aryl Coupling Reactions

轴手性联芳基化合物广泛应用于材料、染料、医药、不对称催化等诸多领域,是一类重要的化合物。过渡金属催化的不对称偶联反应作为经典的合成方法一直是合成化学家关注的对象。本文介绍了过渡金属催化的芳基-芳基偶联反应在轴手性联芳类化合物的立体选择性合成方面的进展。

Axially chiral biaryl derivatives are a class of important chiral compounds widely used in many fields such as materials,dyes,pharmaceuticals,as well as asymmetric catalysis.Transition-metal catalyzed aryl-aryl coupling reactions,as a classical method,have gained extensive attention.Thus,we hope to describe the progress of stereo-selective synthesis of axially chiral biaryl derivatives based on the transition-metal catalyzed aryl-aryl coupling reactions.