替格瑞洛治疗冠心病的效果及导致消化道出血的情况研究

Effects of Tigrillo on coronary heart disease and gastrointestinal bleeding

目的:探讨用替格瑞洛治疗冠心病的效果及导致患者发生消化道出血的情况。方法:选取沭阳县中医院心内科在2018年5月至2019年6月期间收治的80例冠心病患者作为研究对象。将其随机分为替格瑞洛组和氯吡格雷组(40例/组)。为替格瑞洛组患者采用替格瑞洛进行治疗,为氯吡格雷组患者采用氯吡格雷进行治疗。然后比较两组患者治疗的有效率和消化道出血等不良反应的发生率。结果:替格瑞洛组患者治疗的有效率高于氯吡格雷组患者,其消化道出血等不良反应的发生率低于氯吡格雷组患者,P<0.05。结论:用替格瑞洛治疗冠心病可取得较好的临床疗效,能够显著改善患者的临床症状,且不易导致其发生消化道出血,安全性较高。

Objective:To investigate the effect of ticagrelor in the treatment of coronary heart disease and the incidence of gastrointestinal bleeding.Methods:A total of 80 patients with coronary heart disease admitted to the Department of Cardiology,Shuyang Hospital of Traditional Chinese Medicine from May 2018 to June 2019 were selected as the research objects.They were randomly divided into tigrillo group and clopidogrel group(40 cases/group).Patients in the Tigrillo group were treated with tigrillo and those in the clopidogrel group were treated with clopidogrel.Then the effective rate of treatment and the incidence of adverse reactions such as gastrointestinal bleeding were compared between the two groups.Results:The effective rate of tigrillo group was higher than that of clopidogrel group,and the incidence of adverse reactions such as gastrointestinal bleeding was lower than that of clopidogrel group(P<0.05).Conclusion:The treatment of coronary heart disease with Ticagrelor can achieve good clinical efficacy,can significantly improve the clinical symptoms of patients,and is not easy to cause gastroin testinal bleeding,high safety.