丙基硫氧嘧啶联合醋酸泼尼松治疗甲亢的效果研究

Effect of propyl thiouracil combined with prednisone acetate in the treatment of hyperthyroidism

目的:探讨使用丙基硫氧嘧啶联合醋酸泼尼松治疗甲亢的效果。方法:将2018年10月至2019年10月期间云南省普洱市人民医院健康管理中心收治的74例甲亢患者根据抽签法分为研究Ⅰ组(37例)和研究Ⅱ组(37例)。为研究Ⅰ组患者使用甲硫咪唑联合健肝灵进行治疗,为研究Ⅱ组患者使用丙基硫氧嘧啶联合醋酸泼尼松进行治疗。然后观察两组患者治疗的效果及发生肝功能损害的情况。结果:治疗后,研究Ⅱ组患者治疗的总有效率高于研究Ⅰ组患者,P<0.05。治疗后,两组患者肝功能损害的发生率相比,P>0.05。结论:使用丙基硫氧嘧啶联合醋酸泼尼松治疗甲亢的效果显著,但会对患者的肝功能造成损害。

Objective:To investigate the effect of propyl thiouracil combined with prednisone acetate in the treatment of hyperthyroidism.Methods:in October 2018 to October 2019,during a region of yunnan province people’s hospital of 74 hyperthyroidism patients admitted in health management centerⅠaccording to the draw method is divided into study group(37 cases)and the researchⅡgroup(37 cases).As researchⅠgroup of patients using a sulfur imidazole joint health treatment,liver spirit as the researchⅡgroup of patients using propylthiouracil joint treatment with prednisone acetate.Then the effect of treatment and the occurrence of liver function damage were observed in both groups.Results:after treatment,the studyⅡgroup total effective rate of treatment is higher thanⅠgroup of patients,P<0.05).After treatment,the incidence of liver damage in the two groups was compared to P>0.05.Conclusion:The use of propyl thiouracil combined with prednisone acetate in the treatment of hyperthyroidism is effective,but will cause damage to the liver function of patients.