MRI定量研究冈上肌腱损伤程度与脂肪浸润及肌肉萎缩程度的相关性

Correlations between the degree of supraspinatus tendon injury and degrees of fat infiltration and muscle atrophy using the quantitative study of MRI

目的:测量冈上肌腱损伤病人冈上肌脂肪含量及肌肉萎缩程度,研究其与冈上肌腱损伤程度之间的相关性。方法:选取40例肩关节冈上肌肌腱损伤病人及14名健康志愿者(对照组)作为研究对象,均采用3.0T MRI进行常规肩关节MRI检查及脂肪定量扫描(mDixon-Quant)。获取冈上肌脂肪分数图及冈上肌相对大小值。按冈上肌肌腱MRI不同表现将40例病人分为退变组、部分撕裂组和完全撕裂组。分析比较各组间冈上肌脂肪含量及相对大小值,冈上肌脂肪含量及相对大小值与冈上肌腱损伤程度间的相关性。结果:各组间FF值,对照组<退变组<完全撕裂组,对照组<部分撕裂组组<完全撕裂组,差异均有统计学意义(P<0.01),退变组和部分撕裂组差异无统计学意义(P>0.05);冈上肌相对大小,对照组>退变组>完全撕裂组,对照组>部分撕裂组组>完全撕裂组,差异均有统计学意义(P<0.05~P<0.01),退变组和部分撕裂组差异无统计学意义(P>0.05);FF值与冈上肌腱损伤程度呈正相关(rs=0.95,P<0.01),冈上肌相对大小与冈上肌腱损伤程度呈负相关(rs=-0.80,P<0.01),冈上肌相对大小与FF值呈负相关(r=-0.73,P<0.01)。结论:3.0T MRI可定量评价冈上肌脂肪浸润及萎缩程度,同时显示其与肌腱损伤程度的关系。

Objective:To measure the fat content and degree of muscle atrophy in patients with supraspinatus tendon injury,and study the correlations between the degree of supraspinatus tendon injury,and degrees of fat infiltration and muscle atrophy.Methods:Forty patients with supraspinatus tendon injury of shoulder joint and 14 healthy examinees(control group)were investigated.The routine shoulder joint MRI examination and fat quantitative scan(mDixon-Quant)were performed.The fat fraction diagram of supraspinatus and relative size of supraspinatus were obtained.According to the different manifestations of MRI,the patients were divided into the degeneration group,partial tear group and complete tear group.The supraspinatus fat content and relative value,and its correlation with degree of supraspinatus tendon injury among four groups were analyzed and compared.Results:Among four groups,the FF value in the control group,degeneration group and complete tear group,and in the control group,partial tear group and complete tear group gradually increased in turn,and the difference of which was statistically significant(P<0.01).The difference of the FF value between degeneration group and partial complete tear group was not statistically significant(P>0.05).Among four groups,the supraspinatus volume in the control group,degeneration group and complete tear group,and in the control group,partial tear group and complete tear group gradually decreased in turn,and the difference of which was statistically significant(P<0.05 to P<0.01).The difference of the supraspinatus volume between degeneration group and partial complete tear group was not statistically significant(P>0.05).The FF value was positively correlated with the degree of supraspinatus tendon injury(rs=0.95,P<0.01),the relative size of supraspinatus was negatively correlated with the degree of supraspinatus tendon injury(rs=-0.80,P<0.01),and the relative size of supraspinatus was negatively correlated with the FF value(r=-0.73,P<0.01).Conclusions:3.0T MRI can quantitatively evaluate the degree of fat infiltration and atrophy of supraspinatus and show the relationship between the degrees of fat infiltration and atrophy and degree of tendon injury.