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环磷腺苷葡胺对急性ST段抬高型心肌梗死患者心功能的影响

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摘要 目的探讨环磷腺苷葡胺对急性ST段抬高型心肌梗死(STEMI)患者心功能的影响。方法选取2015年10月至2018年10月南阳市第二人民医院收治的STEMI患者72例,依照治疗方案分为常规组与研究组,各36例。常规组采用阿替普酶治疗,研究组采用环磷腺苷葡胺联合阿替普酶治疗。比较两组临床疗效、治疗前后心功能指标[左室射血分数(LVEF)、心脏指数(CI)、心排血量]及不良反应发生率。结果研究组总有效率94.44%(34/36),与常规组83.33%(30/36)比较,差异无统计学意义(P>0.05);治疗后研究组LVEF、CI及心排血量较常规组高,差异有统计学意义(均P<0.05);治疗后研究组血清H-FABP、NT-proBNP、Hcy水平较常规组低,差异有统计学意义(均P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论环磷腺苷葡胺能有效改善STEMI患者缺血再灌注患者的心功能,降低血清H-FABP、NT-proBNP、Hcy水平。
出处 《河南医学研究》 CAS 2020年第24期4525-4527,共3页 Henan Medical Research
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