硫酸镁+硝苯地平治疗妊娠高血压的临床疗效观察

Clinical effect of magnesium sulfate and nifedipine in the treatment of pregnancy induced hypertension

目的:探讨硫酸镁联合硝苯地平治疗妊高症的临床效果。方法:随机将我院收治的100例妊高症患者分成甲乙两组,各50例。分别给予硫酸镁与硫酸镁+硝苯地平联合治疗,对比分析两组治疗效果。结果:甲组治疗总有效率为76%(38/50),同乙组的98%(49/50)相比,差异显著(P<0.05);治疗后乙组收缩压与舒张压显著低于甲组(P<0.05);甲组自然分娩率为50%(25/50),乙组为70%(35/50),甲组并发症总发生率为32%(16/50),显著高于乙组的6%(3/50),两组比较,差异有统计学意义(P<0.05)。结论:硝苯地平联合硫酸镁在妊高症治疗中的应用,不仅可有效控制血压,还能大大降低剖宫产率与并发症发生率,整体效果显著,值得推广。

Objective:To explore the application and effect of magnesium sulfate combined with nifedipine in the treatment of PIH.Methods:100 cases of PIH in our hospital were randomly divided into two groups:50 cases in group A and 50 cases in group B.Results:The total effective rate of group A was 76%(38/50),compared with 98%(49/50)of group B,the difference was significant(P<0.05);after treatment,the systolic and diastolic pressure of group B was significantly lower than that of group A(P<0.05);in addition,the natural delivery rate of group A was 50%(25/50),compared with 70%(35/50)of group B,and the total incidence of complications of group A was 32%(16/50),also significantly higher than that of group B,the difference was statistically significant Meaning(P<0.05).Conclusion:Nifedipine combined with magnesium sulfate in the treatment of PIH can not only effectively control the blood pressure of patients,but also greatly reduce the rate of cesarean section and complications.The overall effect is significant and worthy of promotion.