超短波联合神经松动术对腰椎间盘突出症患者神经传导速度、血清PGE2及β-EP水平的影响

Effect of ultrashort wave combined with nerve mobilization on nerve conduction velocity and serum PGE2 andβ-EP levels in patients with lumbar disc herniation

目的研究超短波联合神经松动术对腰椎间盘突出症患者神经传导速度、血清前列腺素E2(PGE2)及β-内啡肽(β-EP)的影响。方法选取该院68例腰椎间盘突出症患者,随机分为观察组和对照组,每组34例。对照组使用坐骨神经松动术进行治疗,每天2次,持续治疗4周。观察组在对照组的基础上使用超短波进行治疗,每天1次,持续治疗4周。观察和比较两组临床疗效,治疗前后视觉模拟评分(VAS)、患者疼痛介质、神经功能及应激反应的差异,比较两种方法的治疗效果。结果观察组总有效率为97.06%,对照组为76.47%,观察组明显高于对照组,差异有统计学意义(P<0.05)。治疗前,两组的VAS评分,差异无统计学意义(P>0.05);治疗后两组患者的VAS评分均降低,且观察组低于对照组,差异有统计学意义(P<0.05)。治疗前,两组血清中疼痛介质水平、下肢神经传导速度、血清应激激素水平差异无统计学意义(P>0.05)。治疗后,两组血清中疼痛介质水平、下肢神经传导速度、血清应激激素水平较治疗前明显降低,且观察组低于对照组,两组患者血清β-EP水平均高于治疗前,且观察组水平高于对照组,差异有统计学意义(P<0.05)。治疗后,两组血清中皮质醇(Cor)、胰岛素(INS)、去甲肾上腺素(NE)水平均较治疗前明显降低,且观察组低于对照组,差异均有统计学意义(P<0.05)。治疗后,两组神经运动神经传导速度(MCV)和感觉神经传导速度(SCV)均高于治疗前,且观察组高于对照组,差异均有统计学意义(P<0.05)。结论超短波联合神经松动术对腰椎间盘突出症患者具有较好的治疗效果,可提高患者的神经传导速度,降低血清疼痛介质水平,提高血清应激激素水平,具有良好的应用价值。

Objective To study the effects of ultrashort wave combined with nerve mobilization on nerve conduction velocity,serum prostaglandin E2(PGE2)and serumβ-endorphin(β-EP)levels in patients with lumbar disc herniation.Methods A total of 68 patients with lumbar disc herniation were randomly divided into observation group and control group,34 cases in each group.The control group was treated with sciatic nerve mobilization twice a day for 4 weeks.The observation group were treated with ultrashort waves on the basis of the control group,once a day for 4 weeks.The clinical efficacy of the two groups,visual analog score(VAS)before and after treatment and the differences of pain media,neurological function and stress response before and after treatment were observed and compared,and the therapeutic effects of the two methods were compared.Results The total effective rate was 97.06%in the observation group and 76.47%in the control group and the value in the observation group was significantly higher than that in the control group,and the differences were statistically significant(P<0.05).Before treatment,there was no significant difference in VAS scores between the two groups(P>0.05).After treatment,the VAS scores of the two groups were significantly lower,and the patients in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).Before treatment,there was no significant difference in serum pain media content,nerve conduction velocity of lower limbs and serum stress hormone between the two groups(P>0.05).After treatment,serum PGE2 levels were decreased in the two groups and the PGE2 level in the observation group was lower than that in the control group.Theβ-EP levels in the two groups after treatment were higher than those before treatment,and theβ-EP level in the observation group was higher than that in the control group,and the differences were statistically significant(P<0.05).After treatment,the serum levels of Cortisol(Cor),insulin(INS)and Norepinephrine(NE)in the two groups were significantly lower than those before treatment,and the levels in the observation group were significantly lower than those in the control group,and the differences were statistically significant(P<0.05).After treatment,the motor conduction velocity(MCV)and sensory conduction velocity(SCV)were higher than those before treatment,and the values in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).Conclusion Ultrashort wave combined with nerve mobilization has a good therapeutic effect on patients with lumbar disc herniation.It can significantly improve the nerve conduction velocity of patients,reduce the levels of serum pain media,and increase the level of serum stress hormone,which has good application value.