无创呼吸机治疗慢阻肺合并呼吸道衰竭的疗效及对PaCO2影响分析

The Effect of Non-Invasive Ventilator in the Treatment of Chronic Obstructive Pulmonary with Respiratory Failure and Analysis of Its Influence on PaCO2

目的:探究无创呼吸机治疗慢阻肺合并呼吸衰竭的疗效及对血二氧化碳分压(PaCO2)影响。方法:以2017年6月~2019年7月本院治疗的64例慢阻肺合并呼吸衰竭患者纳入本次研究,以随机数字法分为对照组、观察组,每组纳入患者32例,对照组给予常规治疗,观察组应用无创呼吸机展开治疗,对比2组的疗效、PaCO2与pH。结果:治疗前,2组患者的PaCO2与pH指标无显著差异,P>0.05;治疗后,观察组与对照组相比PaCO2与pH指标改善显著,P<0.05;观察组的疗效96.42%较对照组的75.00%高,P<0.05。结论:慢阻肺合并呼吸衰竭患者给予无创呼吸机治疗可显著提升其疗效,维持PaCO2与pH至正常范围。

Objective:To explore the curative effect of non-invasive ventilator in the treatment of COPD with respiratory failure and its influence on PaCO2.Methods:64 patients with chronic obstructive pulmonary disease and respiratory failure treated in our hospital from June 2017 to July 2019 were included in this study.They were divided into control group and observation group by random number method.Each group included 32 patients,the control group was given conventional treatment,and the observation group was treated with a non-invasive ventilator to compare the efficacy,PaCO2 and pH of the two groups.Results:Before treatment,there was no significant difference between the PaCO2 and pH indexes of the two groups of patients,P>0.05;After treatment,the PaCO2 and pH indexes of the observation group were significantly improved compared with the control group,P<0.05;the therapeutic effect of the observation group was 96.42%compared with the control 75.00%of the group was high,P<0.05.Conclusion:The treatment of non-invasive ventilator for patients with COPD combined with respiratory failure can significantly improve its curative effect and maintain PaCO2 and pH to the normal range,which is worth adopting.