糠蜡二十八烷醇一步钙皂化制备工艺的研究

Extraction Process of Octacosanol from Rice Bran Wax by One-Step Calcification and Saponification

以精制糠蜡为原料,通过钙化与皂化一步工艺及无萃取工艺制备二十八烷醇,新工艺简化了现有皂化或酯交换工艺,无废水产生,并降低溶剂消耗成本和溶剂回收能耗。研究了精制糠蜡、氢氧化钙、水的最佳配比,皂化温度,皂化时间等因素对皂化提取过程的影响。结果表明精制糠蜡∶氢氧化钙∶水为10∶2∶3,皂化温度85℃,皂化时间6 h为最佳皂化反应条件,柱式分子蒸馏最佳温度分别为190℃和210℃,二十八烷醇质量分数为93%,三十烷醇质量分数为95%,完全符合医药和食品等行业的需求。

Using refined bran wax as the raw material,octacosanol is prepared by one-step calcification and saponification without extraction process.The new process simplified the existing saponification or transesterification process,produced no waste water,and reduced the solvent’s consumption cost and recovery energy consumption.The optimum ratio of refined bran wax,calcium hydroxide and water were obtained.Effects of temperature and time on the saponification extraction process were also covered here.The results indicated that the optimum ratio was 10∶2∶3,and the best saponification condition was shown as follows,the temperature was 85℃,the time was 6 hours,the optimum temperature of column molecular distillation ranged from 190℃to 210℃,and the contents of octacosanol and triacontanol were 93%and 95%,respectively.The requirements of industries,such as medicine and food,were complied with.