阿司匹林联合丁苯酞软胶囊对急性脑梗死患者的治疗效果研究

Study on the therapeutic effect of aspirin combined with butylphthalide soft capsules on patients with acute cerebral infarction

目的:分析阿司匹林联合丁苯酞软胶囊对急性脑梗死患者的治疗效果。方法:选取罗田县人民医院2018年3月-2020年3月所收治的118例急性脑梗死患者为研究对象。随机分为对照组与观察组,每组例数均为59例。对照组患者采用单纯的阿司匹林药物进行治疗,观察组患者则采用阿司匹林药物联合丁苯酞软胶囊进行治疗。治疗后,对比两组患者血液流变学指标、神经功能损伤程度、生活能力、精神状态以及临床治疗疗效。结果:治疗后,观察组患者红细胞比容、全血比黏度、血浆比黏度、纤维蛋白原水平、神经功能损伤评分、无效率低于对照组,生活能力评分、精神状态评分、治愈率、总有效率高于对照组患者(P<0.05)。结论:阿司匹林联合丁苯酞软胶囊应用在急性脑梗死治疗中的治疗效果显著,具有重要的临床应用意义,值得推广普及。

Objective:To study and analyze the therapeutic effect of aspirin combined with butylphthalide soft capsule on patients with acute cerebral infarction.Methods:118 patients with acute cerebral infarction in Luotian people's Hospital from March 2018 to March 2020 were selected as the research objects.They were randomly divided into control group and observation group,with 59 cases in each group.The control group was treated with aspirin alone,while the observation group was treated with aspirin combined with butylphthalide soft capsules.After treatment,the hemorheology indexes,degree of nerve function damage,living ability,mental state and clinical therapeutic effect of the two groups were compared.Results:After treatment,hematocrit,whole blood viscosity,plasma viscosity,fibrinogen level,neurological injury score and inefficiency in the observation group were lower than those in the control group,while the scores of life ability,mental state,cure rate and total effective rate in the observation group were higher than those in the control group(P<0.05).Conclusion:aspirin combined with butylphthalide soft capsule in the treatment of acute cerebral infarction has significant therapeutic effect,has important clinical application significance,and is worthy of popularization.