泌尿生殖道生殖支原体感染的研究进展

Advances on Mycoplasma genitalium infection in urogenital tract

泌尿生殖道支原体感染是引起非淋菌性尿道炎的主要病原体之一,生殖支原体感染可引起男性尿道炎,女性宫颈炎、盆腔炎、不孕、异位妊娠、早产等疾病,其主要通过与感染者黏膜直接接触传播,诊断方法主要是PCR。支原体耐药形势严峻,阿奇霉素、莫西沙星是目前主要治疗用药。本文对泌尿生殖道支原体感染的流行、感染机制、诊断治疗等方面作一简述。

Mycoplasma genitalium is one of the main pathogens causing nongonococcal urethritis.Mycoplasma genitalium infection usually causes urethritis in males,and cervicitis,pelvic infection,infertility,ectopic pregnancy and premature delivery in females.It is mainly transmitted by directly contacting with the mucosa of the infected person,and the effective detection method is PCR.Drug resistance of Mycoplasma genitalium is severe,and azithromycin and moxifloxacin remain in common usage.In this article,the prevalence,mechanism,diagnosis and treatment of Mycoplasma genitalium infection in urogenital tract are reviewed.