右美托咪定和地佐辛缓解腰麻后寒战的比较

Comparison of the Shivering Between Dexmedetomidine and Dezocine After Spinal Anesthesia

目的比较静脉输注右美托咪定和地佐辛对下肢手术腰麻后寒战的治疗效果。方法选择2017年1-12月腰麻后寒战级别为3~4级的择期下肢手术患者90例,随机均分为右美托咪定组、地佐辛组、生理盐水组,每组30例,用药15 min后评估各组患者寒战的缓解率和恶心呕吐的发生率。结果给药15 min后右美托咪定组、地佐辛组寒战缓解率均高于生理盐水组(P<0.05),右美托咪定组、地佐辛组两组寒战缓解率无统计学差异(P>0.05),右美托咪定组恶心呕吐发生率小于地佐辛、生理盐水组(P<0.05)。结论静注右美托咪定0.5μg/kg和静注地佐辛0.1 mg/kg都可缓解下肢手术腰麻后发生的寒战,右美托咪定组恶心呕吐发生率较低。

Objective To compare the effects of dexmedetomidine and dezocine on shivering after spinal anesthesia in lower limb surgery.Methods From January to December 2017,90 cases of selected lower limb surgery patients with shivering grade 3-4 after spinal anesthesia were randomly divided into Dexmedetomidine group,Dezocine group and saline group.Results After 15 min of administration,the shivering relief rate of Dexmedetomidine group and Dezocine group was significantly higher than saline group(P<0.05).There was no significant difference on shivering relief rate between Dexmedetomidine group and Dezocine group(P>0.05),and the incidence of nausea and vomiting in Dexmedetomidine group was lower than Dezocine group and saline group(P<0.05).Conclusion Intravenous administration of dexmedetomidine 0.5μg/kg and dezocine 0.1 mg/kg could relieve shivering after spinal anesthesia in lower limb surgery,and the incidence of nausea and vomiting in the dexmedetomidine group was lower.