蔗糖铁联合促红细胞生成素治疗肾性贫血的临床效果

Clinical effect of iron sucrose combined with erythropoietin in the treatment of renal anemia

目的探究蔗糖铁联合促红细胞生成素治疗肾性贫血的临床效果。方法选取我院2018年1月至2019年3月收治的100例肾性贫血患者,根据治疗方法的不同分为试验组(50例,常规血液透析+蔗糖铁+促红细胞生成素治疗)和对照组(50例,常规血液透析+蔗糖铁治疗)。比较两组的治疗效果、不良反应发生情况、贫血指标和铁指标水平。结果试验组的治疗总有效率为98.00%,高于对照组的86.00%(P<0.05)。两组的不良反应总发生率比较,差异无统计学意义(P>0.05)。治疗后,试验组的Hb、HCT、SF、SI水平均高于对照组(P<0.05)。结论蔗糖铁联合促红细胞生成素治疗肾性贫血的临床效果显著,能改善患者的贫血指标和铁指标水平,且不良反应发生率低,值得临床推广应用。

Objective To explore the clinical effect of iron sucrose combined with erythropoietin in the treatment of renal anemia.Methods A total of 100 patients with renal anemia treated in our hospital from January 2018 to March 2019 were selected.According to the different treatment methods,the patients were divided into experimental group(50 cases,conventional hemodialysis+iron sucrose+erythropoietin treatment)and control group(50 cases,conventional hemodialysis+iron sucrose treatment).The treatment effect,adverse reactions,levels of anemia indexes and iron indexes were compared between the two groups.Results The total effective rate of treatment in the experimental group was 98.00%,which was higher than 86.00%in the control group(P<0.05).There was no statistically significant difference in the total incidence of adverse reactions between the two groups(P>0.05).After treatment,the levels of Hb,HCT,SF and SI in the experimental group were higher than those in the control group(P<0.05).Conclusion Iron sucrose combined with erythropoietin in the treatment of renal anemia has a significant clinical effect,it can improve patients'anemia and iron indexes levels,and has a low incidence of adverse reactions,which is worthy of clinical promotion and application.