尿道电切术治疗早期膀胱癌的临床效果

Clinical effect of transurethral resection in the treatment of early bladder cancer

目的研究尿道电切术治疗早期膀胱癌的临床效果。方法选取我院2018年1月至2019年1月收治的46例早期膀胱癌患者作为研究对象,按照手术方式的不同将其分为对照组和观察组,每组23例。对照组行传统开放手术治疗。观察组行尿道电切术。比较两组患者的血清炎性因子水平、围术期指标、并发症发生率及复发率。结果术后,两组的血清IL-6、TNF-α及IL-8水平均降低,且观察组低于对照组,差异具有统计学意义(P<0.05)。观察组的手术时间、术中出血量、住院时间、导尿管留置时间及膀胱冲洗时间均优于对照组,差异具有统计学意义(P<0.05)。观察组的并发症总发生率为8.70%,低于对照组的34.78%,差异具有统计学意义(P<0.05)。观察组的复发率低于对照组,差异具有统计学意义(P<0.05)。结论与传统开放手术相比,采用尿道电切术治疗早期膀胱癌患者,手术时间及住院时间更短,术中出血量更少,机体炎性反应更轻,并发症发生率及复发率更低,值得临床推广应用。

Objective To study the clinical effect of transurethral resection in the treatment of early bladder cancer.Methods Forty-six cases of early bladder cancer patients treated in our hospital from January 2018 to January 2019 were selected as the research objects and divided into control group and observation group according to different surgical methods,with 23 cases in each group.The control group was treated with traditional open surgery,and the observation group was treated with transurethral resection.The levels of serum inflammatory factors,perioperative indexes,incidences of complications and recurrence rate were compared between the two groups.Results After operation,the levels of serum IL-6,TNF-αand IL-8 in the two groups decreased,and those of the observation group were lower than the control group,and the differences were statistically significant(P<0.05).The operation time,intraoperative blood loss,hospitalization time,catheter indwelling time and bladder irrigation time of the observation group were better than those of the control group,and the differences were statistically significant(P<0.05).The total incidence of complications in the observation group was 8.70%,which was lower than 34.78%in the control group,and the difference was statistically significant(P<0.05).The recurrence rate of the observation group was lower than that of the control group,and the difference was statistically significant(P<0.05).Conclusion Compared with the traditional open surgery,the operation time and hospitalization time of patients with early bladder cancer treated by transurethral resection are shorter,the amount of bleeding is less,the body inflammatory reaction is lighter,the incidence of complications and recurrence rate are lower,which is worth of clinical promotion and application.