2143例献血者RhD阳性的表型分析

Analysis of Rh phenotypes in 2143 RhD positive voluntary blood donors

目的:探讨2143例RhD阳性献血者的Rh分型。方法:用血清学方法对2143例献血者进行Rh血型鉴定,对RhD阳性的标本进行C、c、E、e和D 5种抗原表型分型。结果:2143例RhD阳性献血者的Rh抗原主要是C、c、E、e。共检测出9种Rh血型表型,按照抗原频率由高至低排序,依次为CCee、CcEe、Ccee、ccEE、ccEe、CCEe、CcEE、ccee、CCEE。结论:选择表型相同的悬浮红细胞进行交叉配血,有助于减少Rh抗体的产生,既可节约交叉配血的时间,又降低了溶血性输血不良反应的发生,从而保障临床输血的有效性。

Objective:Analyze the Rh phenotypes in 2143 RhD+voluntary blood donors among.Methods:The RhD blood group of blood samples from 2143 voluntary blood donors were identified by serologic method;the RhC/c/E/e typing of Rh D positive samples was performed.Results:Nine kinds of Rh blood group were detected in these 2143 donors,the CCee、CcEe、Ccee、ccEE、ccEe、CCEe、CcEE、ccee and CCEE were in turn of antigen frequencies from high to low.Conclusions:Blood transfusion with the same phenotype may reduce the production of Rh antibodies and reduce the blood cross matching time and the incidence rate of adverse reactions in patients with blood transfusion and promote the safety of blood transfusion.