公民逝世后器官捐献及利用的单中心数据分析

Single-center data analysis of organ donation and utilization after citizen's death

目的了解无锡地区公民逝世后器官捐献及利用现状,为促进局部地区器官捐献工作的进一步开展提供思路和依据。方法回顾性分析151例器官捐献者的临床资料,其中器官捐献成功者37例,潜在捐献者114例。分析潜在捐献者捐献失败的原因;收集器官捐献成功者的一般资料;分析器官捐献成功者的器官捐献情况和器官利用情况。结果151例器官捐献者中,器官捐献成功者37例,捐献转化率为24.5%。器官捐献失败者114例,捐献失败的原因分别为家属不同意、未达到捐献状态标准、无充足时间评估和工伤纠纷未解决。器官捐献类别包括34例脑-心双死亡器官捐献(DBCD),3例脑死亡器官捐献(DBD),无心脏死亡器官捐献(DCD)。捐献者死亡原因包括19例颅脑外伤、14例脑卒中和4例其他。37例器官捐献成功者中,以流动人口为主。捐献者共捐献大器官和组织154个,其中大器官124个。人均大器官和组织捐献个数(4.2±1.6)个,人均大器官捐献个数(3.4±1.1)个。154个捐献器官中,利用率为96.7%(149/154),器官分配前4位城市为南京、无锡、苏州、常州。结论无锡地区公民逝世后器官捐献成功率及捐献转化率偏低,应建立局部地区器官捐献工作网络、加大器官捐献宣传力度以及开展协调员技能培训。

Objective To get a knowledge of the current status of organ donation and utilization after citizen's death in Wuxi District,and thereby provide ideas and basis for further development of organ donation work in local areas.Methods Clinical data from 151 organ donors,included 37 successful donors and 114 potential donors,were retrospectively analyzed.The reasons for donation failure of potential donors were analyzed.The general information for successful donors was collected.And the information on organ donation and organ utilization in successful donors were analyzed.Results Among the 151 organ donors,37 were successful donors,with the conversion rate reaching 24.5%.For the 114 donors with failed organ donation,the reasons for failure included family disagreement,failure to meet donation status criteria,insufficient evaluation time,and unresolved work injury disputes.The categories for organ donation included 34 cases of donation after brain death followed by cardiac death(DBCD),3 cases of donation after brain death(DBD),and no case of donation after cardiac death(DCD).The reasons for death of donors includes 19 cases of craniocerebral trauma,14 cases of stroke and 4 cases of others.Among the 37 cases of successful donors,the majority were floating population. A total of 154 major organs and tissues were donated, of which 124 were major organs. Thenumber of major organs and tissues donated per citizen was (4.2±1.6) and the number of major organs donated per citizenwas (3.4±1.1). The utilization rate of the 154 donated organs reached 96.7% (149/154), with Nanjing, Wuxi, Suzhou andChangzhou ranking the top 4 of organ distribution. Conclusions The rate for successful organ donation and conversionafter citizen's death is low in Wuxi District. The organ donation work networks in local areas should be established. Andorgan donation promotion efforts and skills training for coordinators should be developed.