液相色谱-串联质谱法测定植物提取物的研究进展

Research progress on the determination of plant extracts by liquid chromatography tandem quadrupole mass spectrometry

2020年国家实行畜牧业全面减抗、禁抗,寻找到替抗物质对于畜牧业持续稳定发展至关重要。植物提取物因其具有的抗菌、抗氧化等作用成为研究重点,准确测定植物提取物含量至关重要。液相色谱-串联四极杆质谱(liquid chromatography tandem quadrupole-masss pectrometry,LC-MS)技术作为近年来前沿的分离分析检测技术被应用到很多行业。本文综述了近几年LC-MS对植物提取物含量的测定研究,以期为植物提取物作为替抗物质应用到畜牧业中,其用法用量的确定提供技术理论支撑,也为植物提取物含量测定标准建立提供参考。

In 2020, the state will implement a comprehensive reduction and ban of animal husbandry antibiotics. Finding substitute for antibiotics is of great importance to the sustainable and stable development of animal husbandry. Plant extract has become the focus of research due to its antibacterial and antioxidant effects. Accurate determination of plant extract content is very important. Liquid chromatography tandem quadrupole-mass spectrometry(LC-MS) has been applied to many industries in recent years as a frontier separation, analysis and detection technology. This paper reviewed the research on the determination of plant extract content by LC-MS in recent years, in order to provide technical and theoretical support for the application of plant extract as a substitute antibacterial substance in animal husbandry and the determination of its usage and dosage, and also to provide reference for the establishment of the determination standard of plant extract content.