云南省部分食品黄曲霉毒素B1膳食暴露风险评估

Risk assessment of dietary exposure to aflatoxin B in parts foods in Yunnan province

目的评估云南省部分食品中黄曲霉毒素B1(aflatoxinB1,AFB1)膳食暴露风险。方法结合2012~2017年云南省部分地区市售大米及其制品、玉米及其制品等6类主要食品的黄曲霉毒素B1含量数据,以及本省营养监测消费量数据,采用点评估方法对云南省居民AFB1暴露水平进行评估。结果云南省全人群来源于6类食品的AFB1暴露量为1.02×10^-3μg/kgbw,其中来源于大米的AFB1暴露量最高,占总暴露量的50.98%,其次是玉米及其制品,占18.63%。总暴露量为大城市>贫困农村>中小城市>一般农村;云南省居民AFB1膳食暴露量对肝癌发病率的贡献为0.040/10万人;各地区居民暴露边界比(margin of exposure, MOE)值介于144.07~180.85之间。结论云南省AFB1污染状况相对良好,仍需持续关注;6类食物中大米、玉米是云南省AFB1的主要暴露来源。

Objective To evaluate the dietary exposure risk of aflatoxin B1(AFB1) in some foods in Yunnan province. Methods Combined with the aflatoxin B1 content data of 6 major foods such as rice and its products, corn and its products sold in parts of Yunnan province from 2012 to 2017, and the province’s nutrition monitoring consumption data, the AFB1 exposure level of residents in Yunnan was evaluated by a point assessment method. Results The exposure of AFB1 derived from 6 types of food in the whole population of Yunnan province was 1.02×10^–3 μg/kg bw, of which AFB1 derived from rice had the highest exposure, accounting for 50.98% of the total exposure, followed by corn and its products, accounting for 18.63%. The total exposure was large cities> poor rural> small and medium-sized cities> general rural. The contribution of dietary exposure of AFB1 to the incidence of liver cancer in Yunnan province was 0.040 per 100,000. The margin of exposure(MOE) value of residents in various regions was between 144.07–180.85. Conclusion The pollution status of AFB1 in Yunnan province is relatively good, and it still needs continuous attention;rice and corn in the 6 types of food are the main exposure sources of AFB1 in Yunnan province.