肝动脉栓塞术和肝动脉化疗栓塞术治疗原发性肝癌患者的临床疗效

Clinical Efficacy of Transcatheter Arterial Embolization and Transcatheter Arterial Chemoembolization in the Treatment of Patients with Primary Liver Cancer

目的探讨肝动脉栓塞术和肝动脉化疗栓塞术治疗原发性肝癌患者的临床疗效。方法选取2015年5月至2018年5月于广东省韶关市第一人民医院确诊为原发性肝癌患者89例作为研究对象,其中接受肝动脉栓塞术治疗的33例患者为对照组,接受肝动脉化疗栓塞术治疗的56例患者为观察组。比较两组患者治疗后发热、恶心呕吐发生情况,治疗前后生命质量测定量表简表(QOL-BREF)评分、甲胎蛋白(AFP)水平以及不同Child-Pugh分级患者5年生存情况。结果经过不同的治疗后,观察组患者发热率低于对照组,QOL-BREF评分高于对照组,AFP水平低于对照组,观察组Child-Pugh C级患者5年生存率明显高于对照组,差异有统计学意义(P<0.05)。结论肝动脉化疗栓塞术治疗原发性肝癌患者的临床疗效优于肝动脉栓塞术。

Objective To explore the clinical efficacy of hepatic artery embolization and hepatic artery chemoembolization in the treatment of patients with primary liver cancer. Methods A total of 89 patients with primary liver cancer admitted to the First People’s Hospital of Shaoguan from May 2012 to May 2015 were selected as the research objects. Among them, 33 patients who received transcatheter arterial embolization were the control group, and 56 patients who received transcatheter arterial chemoembolization were the observation group. Fever, nausea and vomiting after treatment was compared between the 2 groups after treatment. The QOL-BREF score, alpha-fetoprotein(AFP) level, and the 5-year survival of patients with different Child-Pugh grades were compared between the 2 groups. Results After different treatments, the incidence of fever in the observation group was lower than that in the control group. The QOL-BREF scores of the observation group were higher than the control group, and the AFP level was significantly lower than that of the control group. The 5-year survival rate of the observation group Child-Pugh C patients was significantly higher than that of the control group, and the differences were statistically significant(P<0.05). Conclusion Hepatic artery chemoembolization is superior to hepatic artery embolization in the treatment of patients with primary liver cancer.